Table 1.
Replicon | Replication capacitya | EC50 (nM)b |
|
---|---|---|---|
Transient assay | Replicon cells | ||
JFH1 | 100 | 0.051 ± 0.025 | 0.021 ± 0.004 |
HCV3a1 | 74 ± 44 | 0.25 ± 0.10 | 0.53 ± 0.15 |
HCV3a2 | 19 ± 17 | 0.12 ± 0.09 | 0.14 ± 0.04 |
HCV3a4 | 98 ± 52 | 0.87 ± 0.45 | 1.25 ± 0.5 |
Relative to the parental JFH1 replicon. Values are means and standard deviations.
Half-maximal effective concentrations. Values are means and standard deviations (n ≥ 3).