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Viral titer from mice treated with ST-148 p.o. at 50 mg/kg/dose
| Organ | Mean titer (PFU/g tissue or PFU/ml) | SD | P value vs vehicle |
|---|---|---|---|
| Vehicle | |||
| Spleen | 6.08 × 106 | 3.16 × 106 | |
| Liver | 3.98 × 105 | 4.56 × 105 | |
| Plasma | 1.95 × 106 | 1.39 × 106 | |
| ST-148 TID | |||
| Spleen | 8.20 × 105 | 4.35 × 105 | <0.001 |
| Liver | 4.22 × 104 | 4.11 × 104 | 0.046 |
| Plasma | 6.65 × 105 | 5.44 × 105 | 0.029 |
