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. Author manuscript; available in PMC: 2013 Jan 3.
Published in final edited form as: Am J Psychiatry. 2010 Oct 15;168(1):65–72. doi: 10.1176/appi.ajp.2010.10040567

TABLE 3.

Associations Between Confounding Variables and Childhood Trauma in a Twin Cohort (N=2,127)

Confounding Variable Lifetime Childhood Trauma
Maltreatment by an Adult
Bullying by Peers
Accidents
Mothers’ Reports
Children’s Self-Reports
Relative Risk 95% CI Relative Risk 95% CI Relative Risk 95% CI Relative Risk 95% CI
Individual and socioeconomic factors
 Male 1.49 0.95–2.32 1.25 1.04–1.51 1.16 0.88–1.53 0.93 0.79–1.09
 Socioeconomic deprivation 3.81 2.11–6.88 1.83 1.45–2.31 2.10 1.49–2.97 1.06 0.87–1.30
 IQ 0.97 0.96–0.98 0.99 0.98–1.00 0.98 0.97–0.99 1.00 0.99–1.01
Children’s psychopathology
 Internalizing problems 1.04 1.03–1.06 1.02 1.02–1.03 1.02 1.00–1.03 1.01 0.99–1.01
 Externalizing problems 1.04 1.03–1.05 1.02 1.02–1.03 1.02 1.01–1.02 1.01 1.00–1.01
Genetic vulnerabilities
 Mothers with psychosis syndrome 4.58 2.76–7.61 2.24 1.75–2.88 1.94 1.21–3.11 1.32 0.98–1.77
 Genetic composite riska
  Low 1.44 0.90–2.31 1.09 0.90–1.33 1.12 0.83–1.50 1.11 0.94–1.30
  High 2.97 1.34–6.57 1.57 1.07–2.29 2.69 1.63–4.44 1.50 1.07–2.09
  Highest 3.77 1.78–8.01 1.67 1.14–2.43 3.59 2.40–5.37 0.96 0.62–1.48
a

The target twin’s genetic risk was coded as “low” when the dizygotic co-twin did not report any definite psychotic symptoms; “high” when the dizygotic co-twin reported at least one definite symptom; and “highest” when the monozygotic co-twin reported at least one definite symptom. All groups were compared with the group that had the “lowest” genetic risk, that is, when the target twin’s monozygotic co-twin did not report any psychotic symptoms.