Table 4.
Haplotype | 3DL3* | 3DL3 Exons 7-92 |
2DL3* | 2DL1* | No. Observed |
---|---|---|---|---|---|
I--Consensus | 00201 | 001 | 00302 | 57 | |
00901 | 00201 | 001 | 00302 | 173 | |
00901 | 00201 | 001 | 009 | 1 | |
00902 | 00201v4 | 001 | 00302 | 3 | |
00902 | 00201v | 003 | 00302 | 1 | |
00202 | 00201 | 001 | 00302 | 6 | |
00206 | 00201 | 001 | 00302 | 33 | |
030 | 00201 | 001 | 00302 | 2 | |
010 | 00201 | 001 | 00302 | 23 | |
00201 | 00201 | 001 | 00302 | 2 | |
00207 | 00201 | 001 | 00302 | 4 | |
00801 | 00201 | 001 | 00302 | 2 | |
005 | 00201 | 001 | 00302 | 1 | |
01102 | 00201 | 001 | 00302 | 1 | |
015 | 00201 | 001 | 00302 | 2 | |
00101 | 00101 | 001 | 00302 | 6 | |
01302 | 00101 | 001 | 00302 | 1 | |
01306 | 00101 | 001 | 00302 | 2 | |
01303 | 00101 | 001 | 00302 | 1 | |
II--Consensus | 00101 | 002 | 002 | 40 | |
00101 | 00101 | 002 | 002 | 153 | |
00101 | 00101 | 002 | 008 | 1 | |
00103 | 00101 | 002 | 002 | 1 | |
026 | 00101 | 002 | 002 | 1 | |
01302 | 00101 | 002 | 002 | 3 | |
00102 | 00102 | 002 | 002 | 6 | |
00601 | 00102 | 002 | 002 | 3 | |
01305 | 00102 | 002 | 002 | 3 | |
01307 | 00102 | 002 | 002 | 1 | |
017 | 00102 | 002 | 002 | 6 | |
III--Consensus | 025 | 005 | 001 | 5 | |
025 | 025 | 005 | 001 | 2 | |
031 | 025 | 005 | 001 | 1 | |
029 | 025v | 005 | 001 | 1 | |
027 | 025 | 005 | 001 | 1 |
Based on 74 individuals where the centromeric haplotypes could be defined. Two other individuals carrying expected haplotype structures were not included because it was not possible to determine whether they carried Cen-B1/-B1 or Cen-B1/-B2.
The designation is based on the lowest numbered allele with the consensus sequence in exons 7-9 (Table 3).
Haplotype previously reported (18).
Blue shading marks alleles that differ by one or two nucleotide changes from the consensus allele. Only the exon 7-9 segment of KIR3DL3 is included in this comparison. The 3’ nucleotide sequences of KIR3DL3*00902 (labeled 00201v) and KIR3DL3*029 (labeled 025v) are one nucleotide different from their consensus sequences (Table 3).