. Author manuscript; available in PMC: 2013 May 21.

Published in final edited form as: Chem Res Toxicol. 2012 May 4;25(5):1119–1131. doi: 10.1021/tx3000889

Table 3.

dA-AL-I Adducts in Human Kidney: UPLC-ESI/MS³ versus ³²P-Postlabeling Measurements

Country	Age	Gender	Tissue	UPLC-ESI-MS/MS³ dA-AL-I adducts/10⁸ bases	UPLC-ESI-MS/MS³ dA-AL-Il adducts/10⁸ bases	³²P-Postlabeling dA-AL adducts/10⁸ bases
Taiwan	74	Female	Cortex	96.8	0.4	234
Taiwan	74	Female	Tumor	1.2	N.D.	N.D.
Taiwan	60	Male	Cortex	388	1.0	192
Taiwan	60	Male	Tumor	0.9	N.D.	N.D.
Taiwan	51	Male	Cortex	142	0.7	161
Taiwan	51	Male	Tumor	N.D.	N.D.	N.D.
Taiwan	79	Female	Cortex	8.7	N.D	3.0
Taiwan	44	Male	Cortex	44.8	N.D.	3.9
Taiwan	63	Male	Cortex	170	N.D	73.8
Taiwan	63	Male	Tumor	N.D.	N.D.	N.A.
Taiwan	52	Female	Cortex	28.0	N.D.	3.0
Taiwan	58	Male	Cortex	6.8	N.D.	7.8
Taiwan	58	Male	Tumor	N.D.	N.D.	N.A.
Taiwan	67	Male	Cortex	9.6	N.D.	10.3
Taiwan	67	Male	Tumor	N.D.	N.D.	N.A.
Taiwan	61	Male	Cortex	3.0	N.D.	7.5
Taiwan	61	Male	Tumor	N.D.	N.D.	N.A.

Not detected (N.D.) = < 3 adducts per 10⁹ bases by UPLC-ESI/MS³ or by ³²P-Postlabeling/PAGE

Not analyzed (N.A)