Fig 6.
Inflammatory responses of human reproductive tract epithelial cells induced by MOMP proteosomes. IL-8 secretion (A) and IL-6 secretion (B) by End/E6E7 cells incubated with MOMP proteosomes (10 μg/ml), Pam3CSK4 (0.1 μg/ml), E. coli LPS (0.1 μg/ml), or TNF-α (0.02 μg/ml) for 24 h. Cytokines were measured by ELISA of cell supernatants and expressed as a pg/ml fold change relative to cells incubated with medium alone ± standard error (*, P < 0.05, by a one-sample t test; n = 9). IL-8 (C) and IL-6 (D) induced in THUECs incubated as described above (*, P < 0.05; n = 3).