Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation of GXM-mediated inhibition of LPS-induced signal. GXM binds to FcγRIIB, with consequent SHIP activation and inhibition of the PI3K-Akt pathway. This results in a downregulation of LPS-induced IκBα activation, with a consequent reduction of the hyperinflammatory response.
