Fig 6.

Treatment of M. avium subsp. paratuberculosis-infected bovine monocytes with CpGs ODNs. MACS-purified CD14⁺ bovine monocytes were infected with Mycobacterium avium subsp. paratuberculosis (MAP) (MOI = 5) for 3 h and then treated with CpG ODN 2007 for 18 h. Treatment efficacy is evaluated through quantification of M. avium subsp. paratuberculosis viable counts determined through plating. These experiments were conducted three times, with monocytes isolated from three different animals. Data from a representative animal are shown.