Table 1.

Targeted genes with possible FFA transport roles

Gene(s)	Rationale for selection	Reference(s)
tolC	Prior role in alleviating FFA toxicity; outer membrane component for most MFA-type efflux pumps in E. coli; member of Rob regulon	26, 32, 49–51
acrAB	Member of Rob regulon; confers SDS and decanoate resistance	28–30
fadL	Necessary role in outer membrane import of long-chain FFA; increased expression in microarray data sets	26
prc	Identified role in fatty acid import	26
acrD	Confers SDS resistance	28
acrEF	Confers SDS resistance	28
mdtABCD	Confers SDS resistance; increased expression of mdtD in microarray data sets	25, 28
cmr	Efflux pump; increased expression in both microarray data sets	25
mdtG	Efflux pump; member of Rob regulon; increased expression in both microarray data sets	25, 31
mdtK	Efflux pump; decreased expression in one microarray data set and increased expression in another	25
emrAB	Confers SDS resistance; increased expression in one microarray data sets	25, 28
mdtEF	Confers SDS resistance; increased expression in one microarray data set	25, 28
marA	Overlapping regulon with Rob; increased expression in both microarray data sets	25
soxS	Overlapping regulon with Rob; increased expression in both microarray data sets	25
rob	Activation by FFA; increased expression in one microarray data set	25, 30
ompF	Outer membrane protein; indirectly in Rob regulon; strongly decreased expression in both microarray data sets	25, 33