Table 6.
Susceptibility pattern of RGM in CF patientsa
| Drug | M. abscessus (n = 58) |
M. chelonae (n = 24) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CF (n = 38) |
Non-CF (n = 20) |
Pb | CF (n = 10) |
Non-CF (n = 14) |
Pb | |||||
| No. | % | No. | % | No. | % | No. | % | |||
| AMI | 31 | 82 | 17 | 85 | 1 | 6 | 60 | 7 | 50 | 1 |
| AUG2 | 0 | 0 | 0 | 0 | 1 | 1 | 10 | 0 | 0 | 0.41 |
| FEP | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| FOX | 27 | 71 | 15 | 75 | 1 | 1 | 10 | 0 | 0 | 0.41 |
| AXO | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| CIP | 3 | 8 | 0 | 0 | 0.54 | 0 | 0 | 1 | 7 | 1 |
| CLA | 23 | 61 | 13 | 65 | 0.78 | 8 | 80 | 12 | 86 | 1 |
| DOX | 1 | 3 | 0 | 0 | 1 | 0 | 0 | 1 | 7 | 1 |
| IMI | 2 | 5 | 0 | 0 | 0.54 | 0 | 0 | 0 | 0 | 0.41 |
| LZD | 22 | 58 | 6 | 31 | 0.06 | 7 | 70 | 4 | 29 | 0.09 |
| MIN | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| MXF | 3 | 8 | 0 | 10 | 0.54 | 1 | 10 | 0 | 0 | 0.41 |
| TOB | 4 | 11 | 1 | 50 | 0.65 | 5 | 50 | 12 | 86 | 0.08 |
| SXT | 4 | 11 | 1 | 0 | 0.65 | 0 | 0 | 0 | 0 | 1 |
a
Data are numbers and percentages of susceptible isolates.
AMI, amikacin; AUG2, amoxicillin-clavulanic acid; FEP, cefepime; FOX, cefoxitin; AXO, ceftriaxone; CIP, ciprofloxacin; CLA, clarithromycin; DOX, doxycycline; IMI, imipenem; LZD, linezolid; MIN, minocycline; MXF, moxifloxacin; TOB, tobramycin; SXT, trimethoprim-sulfamethoxazole.
b
Determined by a two-tailed Fisher's exact test.