Table 2.

Similarity of 32 selected isolates of C. tropicalis^a

Patient	Isolates compared	Genotyping difference	Nucleotide difference(s)	Similarity (%)	eBURST result
1	1a and 1c	XYR1: 53–24	215, C-Y; 242, C-Y; 344, T-Y	99.19	4
	1a/1c and 1b	5 alleles	5 alleles		4 versus 6
2	2a and 2b	5 alleles	5 alleles		6 versus singleton
3	3a and 3b	6 alleles	6 alleles		Different singleton
4	4a and 4b	Identical	Identical	100	Identical singleton
5	5a and 5b	XYR1: 53–48	11, Y-T; 14, Y-T; 215, C-Y; 242, C-Y; 344, T-Y	98.65	4
6	6a and 6b	XYR1: 53–24	215, C-Y; 242, C-Y; 344, T-Y	99.19	4
	6a = 6b and 6c	MDR1: 24–87	7, T-Y	99.76
	6a and 6c	XYR1: 53–89	14, Y-C; 344, T-Y	99.46	4 versus singleton
	6b and 6c	XYR1: 24–89	14, Y-C; 215, Y-C; 242, Y-C	99.19
7	7a and 7b	6 alleles	6 alleles		Singleton versus 1
8	8a and 8b	XYR1: 52–84	215, Y-C	99.73	1
9	9a = 9b and 9c	XYR1: 31–3	242, C-Y	99.73	18
10	10a and 10b	XYR1: 19–51	344, Y-T	99.73	6
11	11a and 11b	6 alleles	6 alleles		1 versus 4
12	12a/12b and 12c	5 alleles	5 alleles		1 versus 3
	12a and 12b	XYR1: 52–84	215, Y-C	99.73	1
13	13a and 13b	SAPT2: 4–1	55, W-T; 262, G-R; 310, R-A; 421, C-Y; 215, C-Y	99.06	1
		XYR1: 84–52		99.73
14	14a and 14b	MDR1: 24–87	7, T-Y	99.76	4 versus singleton
		XYR1: 24–89	14, Y-C; 215, Y-C; 242, Y-C	99.19

^aIsolates were obtained from 14 patients with fungemia, according to identical patterns generated by sequencing the fragments of six genes (ICL1, MDR1, SAPT2, SAPT4, XYR1, and ZWF1a) and determining the differences in the genotypes. All gene fragments were submitted to the official MLST website (http://pubmlst.org/ctropicalis/). Isolates from patients 1 to 14 are from UNICAMP. In the “Genotyping difference” column, italicized entries represent the different respective genotypes of the compared isolates (e.g., “XYR1: 53-24” in the first row indicates that 1a has XYR1 genotype 53 and 1c has XYR1 genotype 24).