Figure 2.

A schematic representation of PGC development in mice. A brief outline of PGC specification, migration, and colonization of the gonads in mice is shown schematically. (Green) Blimp1- and Prdm14-positive cells that appear in the most proximal epiblasts. (Lower middle panel) A view of the transverse section of the position indicated by a red bar in the lower left panel. Epi, epiblast; (AVE, anterior visceral endoderm; ExE, extra-embryonic ectoderm; PGCs, primordial germ cells; EM, embryonic mesoderm; ExM, extra-embryonic mesoderm; Hg, hindgut; DA, dorsal aorta; NT, neural tube; NoC, notochord; IM, intermediate mesoderm; NeC, nephrogenic cord.