Table S1A.
Results of Cox proportional hazards model: time to asthma-related hospitalization
| Variable | HR | 95% CI | P value | |
|---|---|---|---|---|
| Fluticasone-salmeterol (1 = yes) | 0.039 | 0.004 | 0.428 | 0.0080 |
| Age (continuous) | 1.159 | 0.826 | 1.625 | 0.3939 |
| Male (1 = yes) | 0.479 | 0.119 | 1.930 | 0.3003 |
| Midwest region* (1 = yes) | 4.703 | 0.502 | 44.096 | 0.1752 |
| South region* (1 = yes) | 6.467 | 0.391 | 106.867 | 0.1921 |
| Charlson index in pre-index period (continuous) | 1.672 | 1.149 | 2.432 | 0.0072 |
| Presence of allergic rhinitis (1 = yes) | 1.312 | 0.329 | 5.236 | 0.7002 |
| Number of SABA canisters (continuous) | 1.540 | 1.029 | 2.305 | 0.0358 |
| Number of OCS prescriptions (continuous) | 1.026 | 0.644 | 1.632 | 0.9153 |
| Number of ICS canisters (continuous) | 0.964 | 0.543 | 1.710 | 0.8999 |
| Number of hospital/ED visits for respiratory-related conditions (continuous) | 1.640 | 1.001 | 2.687 | 0.0497 |
Note:
*
Reference group, East region.
Abbreviations: ED, emergency department; ICS, inhaled corticosteroid; OCS, oral corticosteroid; SABA, short-acting beta agonist; CI, confidence interval; HR, hazards ratio.