Table 1.
Titers of CHIKV-specific neutralizing antibodies at day 30 postimmunization with different VSV recombinants
Mouse no. | PRNT80a |
||
---|---|---|---|
rwt-VSV | VSV-CHIKV | VSVΔG-CHIKV | |
1 | <20 | 320 | 640 |
2 | <20 | 320 | >640 |
3 | <20 | 160 | >640 |
4 | <20 | 320 | 320 |
5 | <20 | 320 | 160 |
6 | <20 | 80 | 320 |
7 | <20 | 80 | 160 |
8 | <20 | 320 | 320 |
Groups of 3.5-week-old C57BL/6 mice were immunized i.m. with 106 PFU of indicated viruses. Neutralizing antibody titers were determined in day 30 postimmunization serum samples using PRNT80.