Table 2.
Studies Showing No Positive Association between Osteoporosis and Periodontal Disease
| Author | Population | Study Design | Risk Estimate | Result |
|---|---|---|---|---|
| Von Wowern et al. (26) | 52 women with osteoporotic fractures | Cross-sectional | OR: 1.00 [95% CI: 0.98–1.02] | Osteoporotic subjects had not less bone mineral content in their jaw bones |
| Shrout et al. (30) | 65 postmenopausal women with no or mild periodontitis | Cross-sectional | OR: 1.16 [95% CI: 0.90–1.49] | Complexity of the trabecular pattern weakly correlated with lumbar spine and femoral BMD |
| Elders et al. (32) | 216 females between 46 and 55 years | Cross-sectional | OR: 1.46 [95% CI: 0.97–2.21] | No significant correlation was observed between probing depth, bleeding on probing, missing teeth, alveolar bone height and bone mass |
| Hildebolt et al. (33) | 135 postmenopausal women aged 41–70 years, no moderate, severe periodontitis | Cross-sectional | OR: 1.4 [95% CI: 0.6–3.1] | Attachment loss was correlated with tooth loss but not with BMD. |
| Weyant et al. (34) | 292 dentate women (average age 75.5 years) | Cross-sectional | OR: 1.56 [95% CI: 0.98–2.02] | No statistically significant association between periodontal disease and systemic BMD |
| Lundstrom et al. (35) | 15 women with osteoporosis, 41 women with normal BMD | Cross-sectional | OR: 1.3 [95% CI: 0.98–1.02] | No statistically significant differences in gingival bleeding, probing pocket depths, gingival recession and marginal bone level |