Table 1.

Phenotypic characteristics of study subjects.

	Cohort A				Cohort B
	PCOS (n=939)		Controls (n=957)		PCOS (n=535)		Controls (n=845)
	N	Median (IQR)	N	Median (IQR)	N	Median (IQR)	N	Median (IQR)
Age	939	28 (24-32)	957	36 (30-43)	535	27 (22-32)^a	845	48 (36-58)
BMI (kg/m²)	939	35.0 (29.1-41.5)^a	957	24.0 (21.5-28.5)	535	31.7 (24.9-39.6)^a	845	26.2 (23.3-30.4)
T(ng/dl)^b [(mmol/liter)]^c	919	71 (59-90)^a [2.5 (2.0-3.1)]	109	25 (19-36) [0.9 (0.7-1.2)]	521	67 (46-88)^a [2.3 (1.6-3.1)]	219	34 (25-52) [1.2 (0.9-1.8)]
DHEAS (ng/ml)^d [(\|amol/liter)]	909	2076 (1446-2899)^a [5.63 (3.92-7.87)]	109	1350 (935-1725) [3.66 (2.53-4.68)]	444^c	2226 (1480-3271)^a [6.04 (4.02-8.88)]	214	1070 (777-1565) [2.90 (2.11-4.25)]
Fasting insulin (μlU/ml) [(pmol/l)]^c	841	22 (15-33)^a [132 (90-198)]	107	10 (8-13.5) [60 (48-81)]	428	14 (7-24)^a [84 (42-144)]	676	11 (7.5-15.8) [66 (45-94.8)]
Fasting glucose (mg/dl) [(mmol/l)]^c	892	88 (83-95) [4.9 (4.6-5.3)]	108	89 (84-93) [4.9 (4.7-5.2)]	435	86 (81-92)^a [4.8 (4.5-5.1)]	701	91.2 (85-98.8) [5.1 (4.7-5.5)]

IQR: interquartile range.

P<0.0001 compared to controls within the same cohort

Hormone assays for the two cohorts were carried out in different labs

Conversion factors: T (ng/dl to mmol/liter) multiply by 0.03467; DHEAS (ng/ml to μmol/liter) multiply by 0.002714; insulin (μIU/ml to pmol/l) multiply by 6; glucose (mg/dl to mmol/l) multiply by 0.05551.

DHEAS values were not available in the PPCOS subjects