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. Author manuscript; available in PMC: 2013 Jan 3.
Published in final edited form as: Genesis. 2011 Apr 1;49(4):295–306. doi: 10.1002/dvg.20731

Fig. 4. Aging reduces the number of β-catenin responsive cells per taste bud, but not the number of each taste cell type, nor the proportion of each cell type expressing β-galactosidase.

Fig. 4

a) Left: The number of β-galactosidase positive cells per taste bud section of circumvallate and fungiform papilla from 10 week-old is significantly greater than that of 25 week-old mice. Right: representative stacks of confocal optical sections reveal the much greater extent of BATGAL reporting (green) in young versus old mice. Student’s t-test, n=5–6 mice. *, p<0.05; ***, p<0.001. Scale bars = 20 µm in all panels. b) By contrast, the number of differentiated type II and III cells per taste bud section does not differ between 10 and 25 week-old mice. Student’s t-test, n=3 mice. c) The proportion of β-galactosidase positive cells expressing each of the cell type markers per taste bud section also does not differ between 10 and 25 week-old mice.