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. 2013 Jan;141(1):85–94. doi: 10.1085/jgp.201210864

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© 2013 Brunet et al.

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Figure 5. — Effect of PDE3 and PDE4 inhibition on I_Ba,L. (A) Mean I-V relationship for effect of combined inhibition of PDE3 (1 µM cilostamide [Cilo]) and PDE4 (10 µM R-rolipram [Rol]) on I_Ba,L (n = 4; *, P < 0.01). (B) Mean I-V relationships for effect of PDE4 inhibition (10 µM R-rolipram) on I_Ba,L (n = 5). (C) Mean I-V relationships for effect of PDE3 inhibition (1 µM cilostamide) on I_Ba,L (n = 7; *, P < 0.05). (D) Effects of PDE inhibition on the negative voltage shift in the I-V relationship of I_Ba,L (*, P < 0.05). Data are presented as mean ± SEM (some errors are smaller than the symbols).