Table 6.
Novel baboon miRNAs categorized by diet and LDL-C. The numbers of predicted target genes, and the 2-7mer seed region for each novel miRNA, are shown
| Chow diet | |||
|---|---|---|---|
| High LDL-C |
Low LDL-C |
||
| ‘Seed’ |
No. of targets |
‘Seed’ |
No. of targets |
| GGGTGCG |
37 |
ACCTCGA |
6 |
| TAAGAAC |
423 |
TGGAATA |
315 |
| TGGACGT |
8 |
TTATAAT |
826 |
| TTGACTA |
111 |
|
|
| Total unique targets |
561 |
Total unique targets |
1079 |
| HCHF diet | |||
| High LDL-C |
Low LDL-C |
||
| ‘Seed’ |
No. of targets |
‘Seed’ |
No. of targets |
| CCCAAAT |
306 |
TTCTGAT |
441 |
| CCCGCGG |
6 |
TGGACGT |
8 |
| AGAGCTT |
575 |
GCGCTGG |
15 |
| TTTTGCT |
149 |
|
|
| ACCTCGA |
6 |
|
|
| CTACCCC |
59 |
|
|
| CTGTGAG |
14 |
|
|
| Total unique targets |
902 |
Total unique targets |
416 |
| Both diets | |||
| High LDL-C |
Low LDL-C |
||
| ‘Seed’ |
No. of targets |
‘Seed’ |
No. of targets |
| ATCAAGG |
147 |
ATCAAGG |
147 |
| CCGCCCT |
14 |
CCGCCCT |
14 |
| TTTTTGC |
349 |
CAGGCAC |
402 |
| CAGGCAC |
402 |
|
|
| TTGTTGC |
179 |
|
|
| Total unique targets | 985 | Total unique targets | 552 |