Table 4.
Gene usage of anti-V3 scFvs
|
scFv |
VH |
|
|
VL |
|
|---|---|---|---|---|---|
| V | D | J | V | J | |
|
1D5C |
IGHV3-23*04 |
IGHD3-10*01 |
IGHJ3*02 |
IGKV3-20*01 |
IGKJ1*01 |
|
1E7B |
IGHV4-31*03 |
IGHD5-24*01 |
IGHJ6*03 |
IGKV3-20*01 |
IGKJ2*01 |
|
1G8C |
IGHV5-51*01 |
IGHD4-11*01 |
IGHJ5*02 |
IGKV2-28*01 |
IGKJ2*01 |
|
3B2C |
IGHV5-51*01 |
IGHD4-11*01 |
IGHJ5*02 |
IGKV1-5*03 |
IGKJ4*01 |
|
3B6C |
IGHV4-b*02 |
IGHD3-10*02 |
IGHJ4*02 |
IGKV1-39*01 |
IGKJ2*02 |
|
3B7C |
IGHV4-b*02 |
IGHD3-10*02 |
IGHJ1*01 |
IGKV3-20*01 |
IGKJ4*01 |
|
3C3C |
IGHV5-51*01 |
IGHD4-11*01 |
IGHJ5*02 |
IGKV3-20*01 |
IGKJ1*01 |
|
3E6C |
IGHV4-59*08 |
IGHD3-10*02 |
IGHJ1*01 |
IGKV1-12*02 |
IGKJ3*01 |
|
3E6B |
IGHV4-b*02 |
IGHD3-10*02 |
IGHJ4*02 |
IGKV1-39*01 |
IGKJ4*01 |
| 3E7B | IGHV5-51*01 | IGHD4-11*01 | IGHJ5*02 | IGKV3-20*01 | IGKJ1*01 |
This table shows the gene usage of the ten anti-V3 scFvs. Nine out of the ten sequences are distinct. Clones 3C3C and 3E7B show similar gene usage which are shown in italic.