Table 2.
Characteristics of the study sample of patients stratified according to the eGFR
| |
Normal eGFR (group 1) |
Mild decreased eGFR (group 2) |
Moderate decreased eGFR (group 3) |
P Values |
|||
|---|---|---|---|---|---|---|---|
| ANOVA or χ2 | group 1 vs group 2 | group 1 vs group 3 | group 2 vs group 3 | ||||
| Age (years) |
56 ± 11.5 |
63,0 ± 11.7 |
70.0 ± 9.4 |
<0.001 |
0.001 |
<0.001 |
0.05 |
| Gender (male/female) |
31/17 |
76/43 |
20/13 |
0.928 |
|
|
|
| Family history of hypertension (yes/no) |
25/23 |
69/50 |
19/14 |
0.778 |
|
|
|
| Family history of stroke (yes/no) |
11/37 |
22/97 |
6/27 |
0.790 |
|
|
|
| Smokers (yes/ex/no) |
13/8/27 |
8/27/7 |
27/75/21 |
0.379 |
|
|
|
| Diabetes (yes/no) |
5/43 |
11/108 |
4/29 |
0.883 |
|
|
|
| Diastolic BP (mmHg) |
73.2 ± 14.0 |
77.3 ± 11.5 |
73.0 ± 9.8 |
0.048 |
0.129 |
1 |
0.185 |
| Systolic BP (mmHg) |
124.5 ± 23.3 |
137.5 ± 20.0 |
130.2 ± 27.3 |
0.002 |
0.002 |
0.754 |
0.286 |
| Pulse pressure (mmHg) |
51.3 ± 14.1 |
60.1 ± 16.9 |
57.3 ± 23.3 |
0.014 |
0.010 |
0.396 |
1 |
| Fasting blood glucose (mmHg) |
99.7 ± 32.2 |
102.8 ± 20.0 |
106.7 ± 23.9 |
0.432 |
1 |
0.589 |
1 |
| Total Cholesterol (mg/dl) |
178.9 ± 36.4 |
187.7 ± 40.8 |
189.0 ± 45.8 |
0.395 |
0.610 |
0.817 |
1 |
| BMI (kg/m2) |
27.4 ± 5.2 |
28.1 ± 4.6 |
26.7 ± 3.5 |
0.261 |
1 |
1 |
0.379 |
| Beta-blockers (yes/no) |
15/33 |
41/78 |
11/22 |
0.924 |
|
|
|
| Alphabeta-blockers (yes/no) |
5/43 |
14/105 |
2/31 |
0.639 |
|
|
|
| Alpha-blockers (yes/no) |
3/45 |
8/111 |
5/28 |
0.252 |
|
|
|
| Diuretics (yes/no) |
17/31 |
49/70 |
21/12 |
0.03 |
|
|
|
| ACE inhibitor (yes/no) |
16/32 |
48/71 |
11/22 |
0.604 |
|
|
|
| Dihydropyridine (yes/no) |
12/36 |
30/89 |
10/23 |
0.826 |
|
|
|
| eGFR (mL/min/1.73 m2) |
101.9 ± 12.0 |
74.3 ± 8.8 |
50.6 ± 8.0 |
<0.001 |
<0.001 |
<0.001 |
<0.001 |
| IMT (mm) |
1.8 ± 0.76 |
2.23 ± 1.21 |
2.91 ± 2.85 |
0.007 |
0.282 |
0.005 |
0.81 |
| Vascular abnormalities (no/ thickening/plaque) |
33/6/9 |
91/13/15 |
28/3/2 |
0.502 |
|
|
|
| LVMi g/m2 |
124.3 ± 26. 2 |
133.0 ± 32.3 |
130.4 ± 32.1 |
0.258 |
0.301 |
1 |
1 |
| Left Ventricular hypertrophy (no/yes) | 24/24 | 44/75 | 12/21 | 0.268 | |||
Data are expressed as mean and standard deviation for continuous variables (i.e. age) and as number of patients per each group for categorical variables (i.e. gender).
The p-values refer to ANOVA and post-hoc comparisons with Bonferroni corrections for continuous variables, to χ2 for categorical variables.