Table 3.
Clinical sample characteristics
|
At enrolment |
At follow up 12 months |
Lost to follow up |
P value* |
Dead |
P value** | |||||
|---|---|---|---|---|---|---|---|---|---|---|
|
n= 546 |
n=411 |
n=91 |
n=44 |
|||||||
| N./mean | %/SD | N./mean | %/SD | N./ mean | %/SD | N./mean | %/SD | |||
| Hypertension |
383 |
70.1% |
277 |
67.4% |
71 |
78.0% |
0.047 |
35 |
79.5% |
0.155 |
| Atrial Fibrillation |
104 |
19.0% |
72 |
17.5% |
15 |
16.5% |
0.814 |
17 |
38.6% |
0.001 |
| Diabetes Mellitus |
118 |
21.6% |
88 |
21.4% |
18 |
19.8% |
0.731 |
12 |
27.3% |
0.341 |
| Previous strokes |
62 |
11.4% |
39 |
10% |
8 |
8.8% |
0.836 |
15 |
34.1% |
<0.001 |
| Previous TIA |
54 |
9.9% |
40 |
9.7% |
4 |
4.4% |
0.103 |
10 |
22.7% |
0.003 |
| Previous AMI |
54 |
9.9% |
38 |
9.2% |
9 |
9.9% |
0.849 |
7 |
15.9% |
0.163 |
| Ischemic |
464 |
84% |
352 |
85.6% |
76 |
83.5% |
0.604 |
36 |
81.8% |
0.540 |
| Bamford Classification § |
|
|
|
|
|
|
0.295 |
|
|
<0.001 |
| PACS |
177 |
32.4% |
126 |
30.7% |
37 |
40.7% |
|
14 |
31.8% |
|
| LACS |
181 |
33.2% |
146 |
35.5% |
29 |
31.9% |
|
6 |
13.6% |
|
| POCS |
82 |
15.0% |
65 |
15.8% |
13 |
14.3% |
|
4 |
9.1% |
|
| TACS |
106 |
19.4% |
74 |
18.0% |
12 |
13.2% |
|
20 |
45.5% |
|
| NIHSS – at admission Mean (SD) |
7.2 |
6.5 |
6.7 |
6.0 |
6.2 |
5.7 |
0.403 |
13.2 |
9.6 |
<0.001 |
| Median (IQR) |
5.0 |
7.0 |
5.0 |
6.0 |
4.0 |
8.0 |
0.157¥ |
13.0 |
14.0 |
<0.001¥ |
| Barthel Index mean-admission |
52.3 |
36.4 |
54.3 |
35.0 |
58.1 |
38.1 |
0.363 |
19.4 |
30.1 |
<0.001 |
| Barthel Index mean-discharge |
67.5 |
36.5 |
70.9 |
33.1 |
68.7 |
35.8 |
0.566 |
26.2 |
37.4 |
<0.001 |
| Barthel Index category at discharge |
|
|
|
|
|
|
0.588 |
|
|
<0.001 |
| Indipendence (96–100) |
189 |
34.6% |
215 |
52.3% |
37 |
40.7% |
|
4 |
9.1% |
|
| Mild dependence (75–95) |
106 |
19.4% |
77 |
18.7% |
17 |
18.7% |
|
3 |
6.8% |
|
| Moderate dependence (46–74) |
84 |
15.4% |
58 |
14.1% |
12 |
13.2% |
|
2 |
4.5% |
|
| Severe dependence (0–45) |
145 |
26.6% |
56 |
13.6% |
24 |
26.4% |
|
27 |
61.4% |
|
| N.A. |
22 |
4.0% |
5 |
1.2% |
1 |
1.1% |
|
8 |
18.2% |
|
| Modified Ranking Scale at discharge |
|
|
|
|
|
|
0.217 |
|
|
<0.001 |
| 0 |
50 |
9.2% |
89 |
21.7% |
8 |
8.8% |
|
4 |
9.1% |
|
| 1 |
133 |
24.4% |
128 |
31.1% |
28 |
30.8% |
|
2 |
4.5% |
|
| 2 |
76 |
13.9% |
41 |
10.0% |
13 |
14.3% |
|
3 |
6.8% |
|
| 3 |
94 |
17.2% |
71 |
17.3% |
18 |
19.8% |
|
1 |
2.3% |
|
| 4 |
131 |
24.0% |
64 |
15.6% |
11 |
12.1% |
|
11 |
25.0% |
|
| 5 | 62 | 11.4% | 18 | 4.4% | 13 | 14.3% | 23 | 52.3% | ||
(§) PACS = Lacunar stroke, PACS = Partial anterior circulation stroke, TACS = Total anterior circulation stroke, POCS = Posterior circulation stroke.
*comparison patients with full follow up (n=411) to lost to follow up (n=91).
** comparison patients with full follow up (n=411) to dead (n=44); ¥ Mann Whitney test.