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. 2013 Jan 3;9(1):e1003111. doi: 10.1371/journal.ppat.1003111

Figure 2. Within-host dominance mirrors the capacity of MCMV strains to ligate Ly49H.

Figure 2

A. Ly49H reporter cell assay. MEF were infected with K181 (positive control) or the C4 strains of MCMV and used to stimulate the Ly49H reporter cell line BWZ-HD12. The percent maximal β-galactosidase production was quantified relative to the PMA/ionomycin control (stippled bar). Both C4A and C4B stimulated β-galactosidase production by reporter cells, whereas C4C and C4D infected cells failed to stimulate β-galactosidase expression. B. Multi-step growth curves for the C4 strains of MCMV. MEF were infected with an MOI of 0.01 and replication rates assessed by plaque assay over a six day period. All viral strains replicated to similar levels in MEF.