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. 2013 Jan 3;9(1):e1003166. doi: 10.1371/journal.pgen.1003166

Figure 4. Body weight, body composition, and food intake of male global adult onset KO mice.

Figure 4

A, Weekly body weight of adult onset KO (n = 15) and vehicle-treated control mice (n = 10), B, Nose-to-anus body length of control (n = 10) and adult onset KO mice (n = 12) at 20 weeks of age, C, Fat mass was increased in adult onset KO mice (n = 14) compared to controls (n = 10) in 9-week old mice (P = 0.05) and further increased in adult onset KO mice (n = 12) compared to controls (n = 10) at 20 weeks, D, Lean mass was reduced in adult onset KO mice (n = 14 and n = 12) compared to controls (n = 10 and n = 10) at both 9 weeks and 20 weeks of age, E, Food intake at 10 weeks of age during a 24-hour period in metabolic cages, control (n = 10) and adult onset KO mice (n = 14). Data are expressed as mean ± SE. In B–E, individual data points are shown. Time-course data were analysed using the repeated-measures ANOVA model, see Materials and Methods (A). The other comparison p-values (B–E), correspond to a Welch t-test of the null hypothesis of no difference between genotypic groups. *P<0.05, **P<0.01, ***P<0.001.