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. 2012 Nov 1;6(6):479–482. doi: 10.4161/chan.22177

graphic file with name chan-6-479-g1.jpg

Figure 1. Example of predicted ionic interactions between positively charged residues on TRPM335–124 (K62, in green) and negatively charged amino acids on CaM (E14, in magenta); the figure was generated from a computer homology model of the 41–70 N-terminal sequence of human TRPM3 based on the structure of the voltage-gated calcium channel CaV1.2 IQ-domain-Ca2+-CaM complex (PDB code 2be6).