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. 2013 Jan 3;8(1):e52720. doi: 10.1371/journal.pone.0052720

Table 2. Correlation between LSM values and other variables.

Independent variables Univariatea Multivariate
r (P-value) β (P-value)
Age, years 0.002 (0.984)
Time since HIV infection diagnosis, months −0.086 (0.412)
Total duration of cART, months −0.011 (0.917)
CD4+ T lymphocyte counts, cells/mm3
At LSM examination −0.186 (0.074) −0.755 (0.452)
Nadir −0.039 (0.714)
Plasma HIV-RNA viral load, copies/mL
At LSM examination −0.017 (0.868)
Log10(highest value after the HIV diagnosis) 0.090 (0.402)
Body mass index, kg/m2 −0.025 (0.819)
Alanine aminotransferase (IU/L) 0.120 (0.251)
Alkaline phosphatase (IU/L) 0.143 (0.170)
Total bilirubin (mg/dL) −0.037 (0.725)
γ-glutamyltranspeptidase (IU/L) 0.119 (0.525)
Prothrombin time, INR 0.181 (0.241)
Platelet count, X 103/mm3 −0.112 (0.287)
Cumulative exposure duration of antiretroviral drugs, monthsb
NRTIs
Zidovudine (n = 68) 0.127 (0.301)
Stavudine (n = 25) −0.247 (0.234)c
Didanosine (n = 39) 0.117 (0.477)
Abacavir (n = 23) −0.059 (0.788)c
NNRTIs (n = 54) 0.230 (0.095)
PIs (n = 58) 0.043 (0.747)
 Boosted (n = 50) −0.241(0.092) −0.234 (0.023)
 Unboosted (n = 31) 0.401 (0.025) 0.430 (<0.001)

NOTE. aPearson’s correlation coefficient, bCorrelation analyses in only patients who has ever been received each antiretroviral drug, cSpearman’s ρ. LSM, liver stiffness measurement; cART, combined antiretroviral treatment; INR, international normalized ratio; NRTIs, nucleoside analogue reverse transcriptase inhibitors; NNRTIs, non-nucleoside analogue reverse transcriptase inhibitors; PIs, protease inhibitors.