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. 2013 Jan 3;8(1):e52982. doi: 10.1371/journal.pone.0052982

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© 2013 Sieber et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Infarct volumes of TREM2-KO and littermate control mice were analyzed at 7 d and 28 d based on Map2 immunohistochemistry. TREM2-KO mice and littermate control mice showed the same relative loss in Map2 immunostaining as a sign of tissue injury. Box and whisker plots represent mean ± s.e.m. (mm³ injured tissue vs. ipsilateral hemisphere in %), n = 9–14 each.