Table II. Results of the label-free quantification. Listed are proteins with an adjusted p value <0.05 and regulation factor (ratio) >1.8 (if applicable). acc. = accession number, SC = sequence coverage (%), SI = spectral index,*number of different peptides, **t-Test p value, ***adjusted p value (correction for multiple testing).

Acc.	Protein	SC	Pep.*	Aggregate (SI)	Control (SI)	Ratio	p value**	Corrected p value***
Q14315	Filamin-C	55.3	101	207.7	29.5	7.0	8.3 × 10−7	5 × 10−5
P17661	Desmin	60.0	24	116.4	29	4.0	5.2 × 10−7	4 × 10−5
A4UGR9	Xin actin-binding repeat-containing protein 2 (Xirp2)	26	83	64.4	0	n.a.	1.9 × 10−6	8 × 10−5
Q86VF7	Nebulin-related-anchoring protein (N-RAP)	21.7	56	49.8	0.8	63.0	6.0 × 10−9	1.2 × 10−6
P02511	αB-crystallin	55.4	8	30.9	3.0	10.3	1.8 × 10−7	1.7 × 10−5
Q5VST9	Obscurin	5.9	57	30.3	10.0	3.0	2.1 × 10−5	0.0006
Q702N8	Xin actin-binding repeat-containing protein 1 (Xin)	21.9	37	30	1.14	25.9	5.4 × 10−8	7 × 10−6
P48681	Nestin	21.7	32	26.8	0.4	67.6	7.0 × 10−7	4.5 × 10−5
P12111	Collagen alpha-3(VI) chain	9.3	30	16.9	3.5	4.4	0.0001	0.003
Q13203	Myosin-binding protein H	35.8	10	16.5	1.1	14.8	0.0009	0.01
Q9UBF9	Myotilin	34.7	18	16	8.7	1.8	0.002	0.02
O75923	Dysferlin	11.4	21	12.7	1.7	7.3	0.0001	0.003
P04792	Heat shock protein beta-1 (Hsp27/HspB1)	38.5	8	12	2.1	5.8	0.0003	0.006
P62805	Histone H4	40.8	4	9.9	3.4	2.95	0.003	0.03
P02545	Lamin-A/C	17.3	12	5.1	0.8	6.5	0.0009	0.01
P08670	Vimentin	18.2	4	4.3	1.0	4.1	0.001	0.02
P28074	Proteasome subunit beta type-5	28.9	6	3.8	0.2	24.6	0.001	0.01
Q86TC9	Myopalladin	5.2	8	3.3	0	n.a.	0.001	0.02
Q0ZGT2	Nexilin	6.8	4	3	0.5	6.2	1.4 × 10−5	0.0004
P13591	Neural cell adhesion molecule 1	3.7	4	2.8	0	n.a.	9.6 × 10−5	0.002
P21333	Filamin-A	2.0	1	2.6	0.3	9.2	7.1 × 10−6	0.0002
Q9H7C4	Syncoilin	8.7	4	1.8	0	n.a.	0.003	0.02
P05023	Sodium/potassium-transporting ATPase subunit alpha-1	11.6	6	1.8	0	n.a.	0.0009	0.01
P28289	Tropomodulin-1	5.8	2	1.4	0.2	8.9	0.002	0.02
P28070	Proteasome subunit beta type-4	13.3	5	1.4	0	n.a.	0.004	0.04
Q0D2I5	Intermediate filament family orphan 1	6.6	3	1.3	0	n.a.	0.0002	0.003
O75369	Filamin-B	3.7	1	1.3	0	n.a.	0.0001	0.003
O43760	Synaptogyrin-2	3.6	3	1.3	0	n.a.	8.7 × 10−5	0.002
P05026	Sodium/potassium-transporting ATPase subunit beta-1	14.2	2	1.1	0	n.a.	1.1 × 10−9	4.3 × 10−7
O00487	26S proteasome non-ATPase regulatory subunit 14	6.5	2	1	0	n.a.	0.001	0.01
Q15286	Ras-related protein Rab35	13.9	1	0.9	0	n.a.	0.0007	0.01