Figure 1. Variety of observed ThS positive inclusions in 4 ALS cases.
ThS positive pathology was observed in lower motor neurons as (a) dash-like or dot-like elements or (b) individual skeins. Multiple skeins could present as (c) a meshwork-like structure or as (d) compact or even Lewy body-like inclusions. (60X, scale bar = 50μm)