FIGURE 9.
Endogenous TSG-6 is not required for the synthesis of leukocyte-adhesive HA cables or induction of HA synthesis by exogenous TSG-6. MASM cells derived from TSG-6−/− mice were either not treated (NT) or treated with only TSG-6, poly(I:C), or the simultaneous incubation of poly(I:C) + TSG-6. The U937 leukocyte binding assay was performed on these cultures (A; n = 4). HA attached to the cells (B; n = 6) and secreted into the media (C; n = 6) was quantified by FACE. Error bars represent S.D.