TABLE 3.

Inhibition of europium-labeled IGF-II binding to IGFBP-2, IGFBP-3, and IGFBP-5 by mature IGF-II and glycosylated IGF-II isoforms (binary complex formation)

Ligand	IGFBP-2		IGFBP-3		IGFBP-5
	IC50	IC50 relative to IGF-II	IC50	IC50 relative to IGF-II	IC50	IC50 relative to IGF-II
	nm	%	nm	%	nm	%
Mature IGF-II	17.59 ± 2.29	100	16.73 ± 4.64	100	12.88 ± 2.13	100
1–87	28.63 ± 4.22	61	15.34 ± 4.39	109	22.37 ± 5.3	58
1–104	26.91 ± 7.77	65	25.09 ± 13.5	67	12.88 ± 2.94	100
1–156	36.76 ± 11.42	48	10.96 ± 2.85	153	14.85 ± 5.27	87