Table 2.
TKI-specific monitoring | Study | Frequency |
---|---|---|
Pazopanib | Urinalysis | Baseline and periodically |
AST (SGPT), ALT (SGOT), bilirubin | Baseline and monthly for 4 months | |
Sunitinib | Echocardiogram | Baseline and as clinically indicated |
Vandetanib | Electrocardiograma | Baseline, at 2–4 weeks and 8–12 weeks, then every 3 months |
If any dose reduction or interruption >2 weeks repeat.