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. 2012 Nov 12;98(1):105–113. doi: 10.1210/jc.2012-2667

Fig. 3.

Fig. 3.

Placental mTORC1 signaling in relation to BMI and birth weight. A, Representative Western blots for total and phosphorylated S6K1 (Thr-389), 4E-BP1 (Thr-37/46 or Thr-70), and RPS6 (Ser-235/236) in homogenates of placentas from pregnancies with varying BMI and birth weights. There was no significant correlation between BMI or birth weight and total S6K1, 4E-BP1, or RPS6. B and C, Relationship between BMI and phosphorylation of placental 4EBP-1 (Thr-37/46) (A) or 4E-BP1 (Thr-70) (B). D–G, Relationship between birth weight and phosphorylation of placental S6K1 (D), RPS6 (E), 4E-BP1 (Thr-37/46) (F), or 4EBP-1 (Thr-70) (G). n = 17; r = Pearson's correlation coefficient.