TABLE 4.
Effect(recessive model) | Odds ratio (95% confidence intervals) | p Valuea |
CTNNA3 rs10762058 (1.1 + 1.2) vs 2.2b | 6.82 (1.65, 28.24) | 0.008 |
Age (years) | 1.10 (1.06, 1.14) | < 0.0001 |
Smoking (current vs. never) | 0.32 (0.15, 0.67) | 0.0024 |
Exposure duration (months) | 1.01 (1.00, 1.01) | 0.0020 |
Note. AW, asymptomatic diisocyanate-exposed controls; DA+, symptomatic exposed workers with SIC-confirmed diisocyanate asthma.
aThe results were adjusted for age, smoking, and exposure duration.
bGenotypes: 1.1, homozygous for the major allele; 2.2, homozygous for the minor allele; 1.2, heterozygous.