. Author manuscript; available in PMC: 2013 Jun 1.

Published in final edited form as: Curr Atheroscler Rep. 2012 Jun;14(3):201–210. doi: 10.1007/s11883-012-0244-1

Table 1.

Loci identified genome-wide as significantly (P < 5 × 10e⁻⁸) associated with coronary heart disease

#	SNP^a	Band	Gene(s)
1	rs11206510	1p32.3	*PCSK9*
2	rs17114036	1p32.2	*PPAP2B*
3	rs599839	1p13.3	*SORT1*
4	rs17465637	1q41	*MIA3*
5	rs6725887	2q33.1	*WDR12*
6	rs2306374	3q22.3	*MRAS*
7	rs12526453	6p24.1	*PHACTR1*
8	rs6903956	6p24.1	*C6orf105*
9	rs17609940	6p21.31	*ANKS1A*
10	rs12190287	6q23.2	*TCF21*
11	rs3798220	6q25.3	*LPA*
12	rs10953541	7q22.3	*DUS4L, BCAP29*
13	rs11556924	7q32.2	*ZC3HC1*
14	rs4977574	9p21.3	*CDKN2A, CDKN2B*
15	rs7025486	9q33	*DAB2IP*
16	rs579459	9q34.2	*ABO*
17	rs2505083	10p11.23	*KIAA1462*
18	rs1746048	10q11.21	*CXCL12*
19	rs1412444	10q23.31	*LIPA*
20	rs12413409	10q24.32	*CYP17A1, CNNM2, NT5C2*
21	rs974819	11q22.3	*PDGFD*
22	rs964184	11q23.3	*ZNF259, APOA5-A4-C3-A1*
23	rs3184504	12q24.12	*SH2B3*
24	rs4773144	13q34	*COL4A1, COL4A2*
25	rs2895811	14q32.2	*HHIPL1*
26	rs3825807	15q25.1	*ADAMTS7*
27	rs216172	17p13.3	*SMG6, SRR*
28	rs12936587	17p11.2	*RSAD1, SMCR3, PEMT*
29	rs46522	17q21.32	*ATP5G1, UBE2Z, GIP, SNF8*
30	rs1122608	19p13.2	*LDLR*
31	rs9982601	21q22.11	*MRPS6*

OR for individual SNP are < 1.10 (about 50%), < 1.20 (about 50%), only two SNP have been attributed reproducible OR > 1.20 (rs3798220 on band 6q25.3 [OR about 1.50] and rs4977574 on band 9p21.3 [OR about 1.30]).

OR–odds ratio; SNP–single nucleotide polymorphism.