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. Author manuscript; available in PMC: 2013 Jan 4.
Published in final edited form as: Nature. 2011 Aug 10;477(7363):207–210. doi: 10.1038/nature10342

Figure 4.

Figure 4

Phylogeny of Toll-like receptor (TLR) families in Atlantic cod. TLR protein sequences were selected based on the conserved TIR domain for Atlantic cod, including known sequences from stickleback, zebrafish, tetraodon, fugu, medaka and human as reference. TLR clades with (*) or without (−) Atlantic cod sequences are denoted according to human or teleost orthologs (summary tree topology, top left). Distance represents the average number of substitutions per site (scale). Maximum Likelihood (ML) values and bayesian posterior probabilities over 75/0.75 support the ML topology. Detailed topologies of TLR 7 (blue) -8 (purple) -9 (green) -22 (grey) show gene expansions for Atlantic cod (red).