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View of the active site. The 2Fo-Fc electron density maps are contoured at 1.5 σ around the GMP in the chain B of WT2 crystal form of Sc-HGPRT. The hydrogen bond network around the GMP molecule is drawn. The hexa-coordinated magnesium is drawn as a sphere colored in cyan. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]
