FIG. 1.
VVWR exhibits tropism for murine reproductive tissue. Groups of three nonpregnant female mice were infected intraperitoneally with 2 × 106 PFU of VVWR. Spleen (SP), liver (LV), uterus (UT), ovary (OV), heart (HT), lymph node (LN), and brain (BR) tissues were harvested 3, 9, or 15 days postinfection and assayed for infectious virus as described in Materials and Methods. Each bar represents vaccinia virus titers within a single organ. Similarly shaded bars represent viral titers in tissues from individual mice.