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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2012 Oct 9;47(6):502–530. doi: 10.3109/10409238.2012.729561

Figure 1. Cartoon illustrating the structures and compositions of typical growth factor and cytokine receptors.

Figure 1

Figure 1

(a) (Left) growth factor receptor, with a kinase domain as an intrinsic part of its cytoplasmic structure. (Right) cytokine receptor, with a signaling kinase noncovalently associated with its cytoplasmic domain. (b) Examples of stiochiometric compositions that have been reported for cytokine and growth factor receptors. Ligands (L) are shown in green, and receptor proteins (α, β or γ) are shown in blue, red or magenta. (A color version of this figure is available in the inline version of this article.)