Table 4.
1. | Testing should be considered in all adults who are overweight (BMI ≥25 kg/m2*) and have additional risk factors: • physical inactivity • first-degree relative with diabetes • high-risk race/ethnicity (e.g., African American, Latino, Native American, Asian American, Pacific Islander) • women who delivered a baby weighing >9 lb or were diagnosed with GDM • hypertension (≥140/90 mmHg or on therapy for hypertension) • HDL cholesterol level <35 mg/dL (0.90 mmol/L) and/or a triglyceride level >250 mg/dL (2.82 mmol/L) • women with polycystic ovary syndrome • A1C ≥5.7%, IGT, or IFG on previous testing • other clinical conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans) • history of CVD |
2. | In the absence of the above criteria, testing for diabetes should begin at age 45 years. |
3. | If results are normal, testing should be repeated at least at 3-year intervals, with consideration of more frequent testing depending on initial results (e.g., those with prediabetes should be tested yearly) and risk status. |
At-risk BMI may be lower in some ethnic groups.