Table 3.
Frequency of Major ARV Mutations Among HIV-Positive Prisoners ever Exposed to an ARV During Incarceration (EPADI) with Genotype Testing in North Carolina Department of Corrections, October 2006 - February 2010 (n=329)
| NNRTI | N | % (95% CI) | NRTI | N | % (95% CI) | PI | N | % (95% CI) |
|---|---|---|---|---|---|---|---|---|
| K103N | 52 | 15.81 (12.0,20.2) | M184V | 47 | 14.29 (10.7,18.5) | I50V | 12 | 3.65 (1.9,6.3) |
| Y181C | 9 | 2.74 (1.3,5.1) | M41L | 16 | 4.86 (2.8,7.8) | L90M | 7 | 2.13 (0.9,4.3) |
| G190S | 4 | 1.22 (0.3,3.1) | K65R | 8 | 2.43 (1.1,4.7) | I54V | 6 | 1.82 (0.7,3.9) |
| K101E | 4 | 1.22 (0.3,3.1) | M184I | 7 | 2.13 (0.9,4.3) | M46I | 6 | 1.82 (0.7,3.9) |
| K103S | 4 | 1.22 (0.3,3.1) | L74V | 6 | 1.82 (0.8,3.9) | I84V | 5 | 1.52 (0.5,3.5) |
| G190A | 3 | 0.91 (0.2,2.6) | L74I | 5 | 1.52 (0.5,3.5) | V82A | 5 | 1.52 (0.5,3.5) |
| K101P | 3 | 0.91 (0.2,2.6) | T215F | 5 | 1.52 (0.5,3.5) | N88D | 4 | 1.22 (0.3,3.1) |
| K238T | 3 | 0.91 (0.2,2.6) | T215Y | 5 | 1.52 (0.5,3.5) | D30N | 3 | 0.91 (0.2,2.6) |
| L100I | 3 | 0.91 (0.2,2.6) | T69ADNT | 3 | 0.91 (0.2,2.6) | I54L | 2 | 0.61 (0.1,2.2) |
| Y188L | 3 | 0.91 (0.2,2.6) | T69NT | 2 | 0.61 (0.1,2.2) | V32I | 2 | 0.61 (0.1,2.2) |
| V106M | 2 | 0.61 (0.1,2.2) |
Mutations with only a single occurrence were M230L, V106A, T69AT, V75T, Y115F, F53L, G48V, G73S, G73T, I47V, I50L, L23I, M46L, and V82T.
NNRTI, nonnucleoside reverse transcriptase inhibitors; NRTI, nucleoside reverse transcriptase inhibitors; PI, protease inhibitors.