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Examples of plots of inhibition of thrombin binding to immobilized polyP for 4 selected inhibitors. The percent inhibition of thrombin binding to polyP is plotted for the following inhibitors that encompassed a range of IC50 values: low MW polyethyleneimine (▿), generation 1.0 PAMAM dendrimer (■), polymyxin B (□), and spermidine (▴). The dotted line represents 50% inhibition. Data are mean ± SE (n = 3).
