Table 1.

Clinical characteristics of patients with T-LGL

T-LGL Leukemia Cohort	Splenomegaly	No Splenomegaly	p-Value
Total Number in Cohort (Female)	34 (16)	22 (8)	0.61
Median Age at Diagnosis in Years (Range)	64 (28–81)	64 (31–78)	0.88
Single Lineage Cytopenia	10/34 (29%)	15/22 (68%)	<0.01
Anemia (Hgb<10g/dL)	8/34 (24%)	9/22 (41%)	0.17
Neutropenia	1/34 (3%)	5/22 (23%)	0.02
Thrombocytopenia	1/34 (3%)	1/22 (5%)	0.75
Bicytopenia	16/34 (47%)	3/22 (14%)	<0.01
Pancytopenia	8/34 (24%)	3/22 (14%)	0.36
Median LGL Count (Range)	1800 (100–20575)	1130 (100–7410)	0.41
Median CD4:CD8 (Range)	0.35 (0.03–3.00)	0.31 (0.04–1.39)	0.51
Median % Vβ expansion (Range)	63 (19–98)	64 (11–90)	0.88

Splenomegaly was identified by palpation or clinical suspicion and confirmed by ultrasound or CT scan.