Skip to main content
. Author manuscript; available in PMC: 2013 Jan 4.
Published in final edited form as: J Immunol. 2011 May 13;186(12):6683–6692. doi: 10.4049/jimmunol.1100525

Figure 4. TAP and ERAAP regulate class II-restricted listerial Ag presentation.

Figure 4

(a) B6, B6.129-TAP0, B6.129-ERAAP0 or B6-129-Ab0 mice were inoculated with L. monocytogenes or delivered PBS i.p. and boosted 2 weeks later. Two weeks after boost, immune splenocytes were stimulated with the indicated peptides for 48hrs and IFN-γ response by TH cells was monitored by ELIspot assay. (b) 129S6/SvEvTac, B.129-TAP0, 129-ERAAP0 or 129-Ab0 mice were primed and boosted as in (a). Two weeks after boost, immune splenocytes were stimulated with the indicated peptides for 48hrs and IFN-γ was monitored by ELIspot assay. Data represents 2 similar experiments using 3—4 mice/group; ± sem.