Table 3.
Multivariate analysis for the complete case, multiple imputation and sensitivity analysis, with M = 1000 imputed data sets
| Complete Case (CC) | Multiple Imputation (MI) | Sensitivity Analysis (SA) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |
Missing values % |
aOR 95% CI |
SE |
CV (%) |
aOR 95% CI |
SE |
CV (%) |
VRMI(MI vs CC)(%) |
δ |
aOR*95% CI |
SE |
CV (%) |
VRSA(SA vs MI)(%) |
| Alcohol consumption |
11.1 |
2.32 |
0.39 |
17 |
2.82 |
0.37 |
13 |
21.86 |
-0.40 |
2.86 |
0.37 |
13 |
1.29 |
| |
|
[1.66,3.23] |
|
|
[2.18,3.66] |
|
|
|
|
[2.21,3.70] |
|
|
|
| Genotype3 |
26.3 |
1.51 |
0.24 |
16 |
1.66 |
0.23 |
14 |
9.70 |
0.15 |
1.60 |
0.21 |
13 |
3.56 |
| |
|
[1.10,2.07] |
|
|
[1.27,2.16] |
|
|
|
|
[1.23,2.06] |
|
|
|
| HIV |
16.3 |
1.56 |
0.41 |
27 |
1.80 |
0.34 |
19 |
15.52 |
0.70 |
1.91 |
0.36 |
19 |
6.12 |
| serostatus | [0.92,2.62] | [1.24,2.61] | [1.32,2.76] | ||||||||||
Note. aOR, odds ratio adjusted on sex, age, duration of HCV infection, alcohol consumption and HIV serostatus; aOR*, odds ratio obtained from the MI adjusted odds ratio estimates.
CI, confidence interval; CV, coefficient of variation of the aOR; VRMI , variation rate of the aOR for CC and MI analyses; VRSA , variation rate of the aOR for MI and senstitivity analyses.
Covariates included in the model were: sex, age, duration of HCV infection, alcohol consumption, genotype 3 and HIV serostatus. Sensitivity analysis: the weighting process was applied to alcohol consumption, genotype 3 and HIV serostatus indepedently.