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. 2013 Jan 4;8(1):e53430. doi: 10.1371/journal.pone.0053430

Figure 4. JunB regulates proteins involved in acto-myosin interactions.

Figure 4

(A) JunB silencing in BSMC significantly reduces basal and TGFβ1-stimulated levels of Rho-kinase (ROCK1) and phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at two activating Thr residues without affecting total protein levels. Representative immunoblots are shown in (B). (C) Total and phosphorylated myosin regulatory light chain (MLC20) levels are reduced upon JunB knockdown. *p<0.05. Representative immunoblots are shown in (D).