Table 3. Associations between cytomegalovirus (CMV) disease and mannan-binding lectin (MBL)/ficolin levels.

Effect	Odds ratio	95% CI
A
MBL, log10 ng/mL	1.03	0.73–1.45
H-ficolin, log10 ng/mL	0.89	0.26–3.03
L-ficolin, log10 ng/mL	2.34	0.44–12.36
M-ficolin, log10 ng/mL	0.66	0.28–1.52
B
MBL, log10 ng/mL	0.85	0.55–1.30
Age1, years	1.03	0.67–1.59
Female gender	2.13	0.84–5.41
HIV RNA, log10 copies/mL	1.53	1.08–2.16
Duration of HIV-infection, years	0.91	0.84–0.98
C
Effect of MBL per log10 ng/mL
CD4 T-cell count ≤20 cells/mm3	0.92	0.60–1.41
CD4 T-cell count >20 cells/mm3	1.26	0.69–2.28
D
Effect of MBL per 100 ng/mL
≤100 ng/mL	0.71	0.12–4.15
100–500 ng/mL	1.17	0.83–1.65
>500 ng/mL	0.99	0.96–1.01

Abbreviations: MBL, mannan-binding lectin; CI, confidence interval.

¹Per 10 years increase.

A) Univariable conditional logistic regression models for MBL, H-ficolin (3), L-ficolin (2) and M-ficolin (1). B) Multivariable conditional logistic regression model for MBL adjusted for the effects of potentially confounding risk factors for CMV disease based on 89 case-control pairs without missing data. C) Conditional logistic regression model for MBL, investigating its relationship with CD4 T-cell count. D) Conditional logistic regression model with a linear spline for MBL.