Table 3. Clinical features of the three patients with citrus fruit allergy.

PATIENT DATA	Patient	1	2	3
	Sex	F	M	M
	Age yrs	20	20	12
	Respiratory disease (A/RC)	A, RC	A, RC	RC
	Symptoms with citrus fruits	Urticaria Vomiting (Orange)	OAS (Orange)	Abdominal pain Diarrhoea (clementine)
	Food Allergy/ OAS to other foods	apple, nuts, tomato	kiwy, melon, strawberry	kiwy
PRICK-TO-PRICK WITH FRUIT PULP Mean wheal diameter (mm)	Orange	7	4	0
	Clementine	6	3	3
	Lemon	6	0	0
SPECIFIC IGE (KU/L)	Orange	39.2	<0.10	4.3
	Wheat	14.3	<0.10	6.5
	Apple	45.7	<0.10	24.4
	Peanut	47.8	<0.10	13.1
	Phleum p.	87.8	14.3	83.9
	Olea e.	56.8	0.8	33.3
	Betula v.	>100	<0.10	57.3
	Corylus a.	92.7	0.4	59
	r Phl p 1	41	15.1	71.2
	r Phl p 12	34.2	0.31	4
	r Bet v 2	47	<0.10	7.1
	r Pru p 3	19.7	<0.10	16.6
	MuxF3-CCD	1.23	<0.10	0.74

Patient data, results of prick-to-prick (PPT) with fresh citrus fruit pulp and specific IgE (sIgE) against the main pollens, (Phleum p., Olea e., Betula v., Corylus a.), fruit extracts (orange, apple, peanut, wheat), recombinant allergens (rPhl p 1, rPhl p 12, rBet v 2, rPru p 3) and MuxF3-CCD.

A: Asthma; OAS: oral allergy syndrome; RC: rhino-conjunctivitis; yrs: years.