Table 1.
Epitope | Predicted HLA Class II Binding Alleles |
---|---|
MAGE-A3112-127 |
DRB1*04, *08, *11, *13, DRB5*01 |
MAGE-A3121-136 |
DRB1*04, *07, *08, *11, *13, *15, DRB5*01 |
MAGE-A3143-160 |
DRB1*01, *03, *04, *07, *08, *11, *13, *15, DRB5*01 |
IL-13Ra2341-355 |
DRB1*01, *03, *04, *07, *08, *11, *13, *15, DRB5*01 |
IL-13Ra2351-365 |
DRB1*01, *03, *04, *07, *08, *11, *13, *15, DRB5*01 |
MBP85-99 | DRB1*01, *03, *04, *08, *11, *13, *15 |
Putative HLA-DR binding was determined using the ProPred MHC Class-II binding peptide prediction server, and emphasizes the promiscuous binding of the MAGE-A3 and IL-13Rα2 peptides used in this study.