Table 2.

Summary of the mild hyperthermia sonications performed in vivo and in vitro. All sonications were performed at a frequency of 1.45 MHz. Duration of 5 min was used for sonications in vivo and 10 min for sonications in vitro.

	Sonication type	Treatment cell size (mm)	Target tissue	Acoustic power (W)	Number of sonications	Focal depth from skin (mm)
Rabbit	Single focus	8.0	Tumor	25.0	5	30
Rabbit	Multifoci	8.0	Tumor	25.0	5	30
Rabbit	Single focus	8.0	Muscle	25.0	5	15
Rabbit	Multifoci	8.0	Muscle	25.0	5	15
Phantom	Single focus	4.0, 8.0, 12.0, 16.0	…	25.0	5, 5, 5, 5	40
Phantom	Multifoci	4.0, 8.0, 12.0, 16.0	…	25.0	5, 5, 5, 5	40